Abstract
Objective: To analyze the hematological profile of children with severe acute malnutrition.
Study Design: Descriptive cross sectional study
Place and Duration: Six months from 1st January 2018 to 1st July 2018 at Nutrition Stabilization Centre of The Children’s Hospital and
Institute of Child Health Multan
Methodology: The hematological profile was of children with severe acute malnutrition (SAM) was done by using EDTA anti
coagulated samples on a five parts differential hematology analyzer Abacs-5 (Diatron) that works on the principle of Electrical
Impedance. Focus was to analyze the values of RBC, HB, WBC and Platelets, Bicytopenia and Pancytopenia.
Results: Data of 100 children was analyzed. There were 58% male and 42% were female. About 34% children were under 6 month of
age. Altered hematological profile of children with severe acute malnutrition was observed. Red blood cells count, WBCs and
platelets count in blood of majority were significantly low than normal, 56%, 50% and 66% respectively. About 28% children had two
cell lines depressed (Bicytopenia) and 48 % children showed three hematological cell line suppressed (pancytopenia). Children with
SAM had lower mean hemoglobin, hematocrit and red cell indices .The mean ± (S.D) of hemoglobin was 8.703 ± (1.9271). There
were 88% children with severe acute malnutrition that are suffering from anemia from which 27% children had mild anemia, 46%
children had moderate anemia and 15% children had severe anemia and 12% children had no anemia.
Conclusion: Altered blood profile was found in children with Severe Acute Malnutrition. There was also a high prevalence of anemia
in malnourished children as compared to general population. Majority of SAM children has markedly less Red Blood cell count,
White blood cell count and platelet count presented with bicytopenia and pancytopenia.
Saadia Khan, Zelle Rubab, Sajjad Hussain, Asad Abbas, Reema Arshad, Muhammad Burhan Khan Tareen. (2020) Hematological profile of children with severe acute malnutrition at the Tertiary care hospital in Multan, Isra Medical Journal, Volume 12, Issue 1.
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