Abstract
Objective: To assess the effects of energy drinks on the micrometric measurements of pancreas of Wistar Albino rats.
Methods: This experimental study was conducted in the Department of Anatomy, in collaboration with the animal house of
Basic Medical Sciences Institute (BMSI), Jinnah postgraduate medical center (JPMC), Karachi from September to October
2018. Thirty adult male Wistar Albino rats were equally divided into three groups (Group A as control, while groups B and C
were administered 7.5ml and 15ml orally for four weeks, respectively). Pancreas was dissected out at the end of study. After
tissue processing, slides were made and stained with hematoxylin and eosin stain (H&E) to observe the morphology and
cytoarchitecture of the tissue.
Results: The findings of the study revealed that the mean diameter of pancreatic acini and islets were significantly lower in
Group B (12.70 ± 1.20), (63.52 ± 8.98) as compared to Group A (26.29 ± 4.37), (123.66 ± 22.08) respectively, p-value <0.05.
Diameter of pancreatic acini and islets were significantly less in Group C (10.06 ± 0.89), (44.58 ± 7.66) as compared to both
Groups A (26.29 ± 4.37), (123.66 ± 22.08) and Group B (12.70 ± 1.20), (63.52 ± 8.98) respectively, p-value <0.01. The
parenchyma of the observed organ was also damaged with loss of normal cytoarchitecture as observed on microscopy.
Conclusion: The results obtained in the current study suggest that consumption of energy drinks seriously damages the
regular anatomy of the pancreas of Wistar Albino rats
Fatima Rehman, Zia-Ul-Islam , Sama-ul-Haq, Lubna Faisal, Sadia Rehman, Santosh Kumar. (2020) Morphometric Study on the Energy Drink Induced Pancreatitis on Wistar Albino Rats, Journal of the Dow University of Health Sciences, Volume 14, Issue 3.
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