Abstract
OBJECTIVE: To determine the association of 2-hour plasma glucose (2h-PG) duration with lipid profile in
families suffering from diabetes mellitus type-2with impaired lipid metabolism.
METHODOLOGY: A cross sectional experimental study was conducted for the duration of thirteen
months. Sample size was 274 (n=274), Subjects with predisposed background of Type 2 diabetes were
evaluated for the relationship between hyperglycemia and lipid profile, for this blood samples from
father, mother and siblings were taken. The data is presented according to 2-hour plasma glucose in
blood.
RESULTS: The persons those are suffering from diabetes type-2 show the mean values of 2H-PG =
250.17, SD=26.81. Total cholesterol=236.50, SD=19.35, correlation coefficient=0.81, P: 2-tailed=0.00.
HDL=47.03, SD=4.33, correlation coefficient= -0.21, P: 2-tailed= 0.00; LDL=179.04, SD =21.96, correlation
coefficient=0.73, P: 2-tailed= 0.00; VLDL=39.84, S.D =6.62, correlation coefficient=-0.10, P: 2-tailed= 0.00;
Total Cholesterol / HDL=5.08 S.D=0.73, correlation coefficient=0.62, P: 2-tailed= 0.00;
Triglycerides=184.99, SD=25.35, correlation coefficient=0.78, P: 2-tailed= 0.00; FPG=193.28, SD =20.14,
correlation coefficient=0.06, P: 2-tailed=0.00, HbA1C =6.81, SD =0.71, correlation coefficient=0.29, P:
2-tailed = 0.00, BMI=25.54, SD =2.06, correlation coefficient=0.37, P: 2-tailed= 0.00.
CONCLUSION: We concluded that diabetic patients have the high risk of developing various diseases
including CVD, therefore in order to prevent from more complications observance of lipid guidelines is
very important for improvement of disease.
Latafat Ali Chughtai, Jawaid Ahmed Zai, Zaib u nisa Mughal, Benazir Faheem. (2018) Association of 2-hour Plasma Glucose (2H-PG) with Lipid Profile in Selected Diabetic Families from Hyderabad Sindh Pakistan, Journal of Liaquat University of Medical and Health Sciences, Volume-17, Issue-4.
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