Abstract
Chemiluminescence (CL) in conjuction with flow injection analysis (FIA) shall be used to tide investigate the biotechnological potential of tris(2,2’-bipyridyl) ruthenium (II) system. CL using the Tris (2,2’-bipyridyl) ruthenium (II) system allows the development of methodologies for the analysis of nicotine amide adenine dinucleotide (NADH) and NAD-NADH converting biocatalyst(enzymes, dehydrogenase) and their substrates using immobilized biocatalyst. For example the analysis of lactate dehydrogenase and its isoenzyme is important for the diagnosis of myocardial; infarction. Certain hormones e.g. thyroxine inhibit glutamate dehydrogenases of Thyroxine and intern provide ways to treat goiter and thyroid cancer which is common in Pakistan. CL-FI manifold provide the ways to improve the sensitivioty,speed and cost effectiveness of clinical assays for hormones/drugs wittout using radioactivity.
Abdul Waseem. (2006) Biotechnological Potential of TRIS (2, 2’ –bipyridyl) ruthenium (II) Chemiluminescence Using Immobilized Enzymes with Flow injection analysis, Journal of Applied and Emerging Sciences, Volume 1, Issue 1.
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