Abstract
Background: The versatile and dynamic activities of Panax Ginseng are attributed to its active components. They
are readily available over the counter and are known for their effects as an aphrodisiac & health building; in
addition, they are given rather generously during pregnancy, as they are considered virtuous for the baby and
mother. Despite its easy availability and excess usage, little is known about its effects on the fetus. The current
experimental design was focused towards the lack of differentiation and inhibition of cell growth of mesodermal
derivatives inflicted by PanaxGingex.
Methods:18 pregnant albino dams were randomly divided into three groups; Group A was control, Group B was
Low dose and Group C was labelled as High dose groups. Tissues (bone, kidney and blood) were selected as
derivatives of paraxial, intermediate and lateral plate mesoderm respectively and were used for light microscopic
study.
Results and Conclusion: The light microscopic examination demonstrated extensive apoptosis and an escalation of
angiogenesis. Both the histological findings were not only statistically significant but was clearly indicative of
dysmorphogenesis. The results of present study raise a finger towards the un-supervised practice of over the counter
preparations especially during the vital antenatal period of development.
Uzma Daud, Qasim Muneer, Javeria Noor, Fahad Raza, Sarah Khalid. (2019) Mesodermal Dysmorphogenesis of Ginsenosides: An Experimental Study, Journal of Shalamar Medical and Dental College, volume 1, issue 1.
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