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Objectives: The aim of our study is to evaluate the possible association of serum magnesium in diabetic patients with and without retinopathy. Study Design: Crosssectional observational. Setting: Bahawal Victoria Hospital, Bahawalpur. Period: September, 2018 to May, 2019. Material & Methods: A total of 258 subjects were enrolled in the study. They were divided in 3 groups, which comprised of 208 diabetic patients; 92 with retinopathy, 116 without retinopathy and the control group comprised of 50 healthy individuals. Both cases and controls were subjected to blood tests for the estimation of biochemical parameters. Results: A considerable decrease was observed in the serum magnesium level of diabetics in comparison with the healthy participants. The mean serum magnesium levels amongst the groups were 1.5 ± 0.2 mg/dl and 2.4 ± 0.3 mg/dl respectively (p<0.001). There was also a marked variation in serum levels of magnesium among diabetic retinopathy patients and diabetics without complications i.e.1.3±0.1 mg/dl and 1.69±0.1 mg/dl respectively (p<0.001). Conclusion: Patients suffering from diabetic retinopathy displayed significantly lower serum magnesium levels in contrast to the control group and diabetics without retinopathy.

Sadiq Hussain, Sara Reza, Hashim Raza, Saleha Zafar, Sami Ahmad, Riaz Ahmed Javed. (2020) Study of Serum Magnesium levels in diabetic patients with and without retinopathy., The Professional Medical Journal, Volume 27, Issue 12.
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