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BACKGROUND: Vitamin E is a fat soluble vitamin and plays key role in many body systems. It
has been in clinical practice for mastalgia for decades, however there is still limited literature
defining its précise role.
METHODS: This case series was retrospectively collected from a prospectively established database of a dedicated breast clinic for a period of 16 months. A total of 100 patients came with a
complaint of breast pain; 20 patients excluded as 17 were having palpable lump while 3 were
post menopausal. Eventually 80 patients were included in this study. They were given Vitamin E
400mg a day for six months. They were followed up at six weeks then at three months and
finally after six months. Patients were given a pain chart to mark severity of pain on daily basis.
RESULTS: Follow up initially at six weeks, three and six months suggested significant
improvement in the symptoms of cyclical mastalgia (p<0.001).
CONCLUSION: Vitamin E is relatively safe supplement with a better compliance, therefore can
be safely considered as first line management of mastalgia in premenopausal young patients.
Champa Sushel, Binafsha Manzoo Syed, Ahmad Khan Sangrasi, Jawaid Naeem Qureshi, Altaf Hussain Talpur. (2016) Role of Vitamin E in Mastalgia in Young Women, Journal of Liaquat University of Medical and Health Sciences, Volume-15, Issue-2.
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