تلخیص
Study Background: The novel corona virus (COVID -19) is a known virus in current pandemic. Clinical
presentation ranges from asymptomatic to severe respiratory and multiple organ failure2
.Large number of SARSCOV2 cases are documented as asymptomatic or with mild illness. To determine the extent of infection,
serological evidence of SARS-COV2 antibodies is warranted
Objectives of the Study: To study the Seroprevalence of covid-19 antibodies among hospitalized patients and to
determine the cumulative immunity in hospitalized patients.
Methodology: This cross-sectional observational study was conducted at United hospital and Creek General
Hospital, Karachi during the duration from December 2020 to February 2021. The study was approved by
institutional ethical review board. Probability convenience method of sampling was used to collect blood
samples. Patients of both genders having age group ranging from 1-80 years or above were included. These
patients were asymptomatic and admitted due to non- COVID 19 reasons. Rapid test was used to detect SARSCOV2 IgM/IgG antibodies. Statistical analysis of data was performed by using SPSS-22. Age is organized into
different subgroups. Chi-square test was applied to determine the significance between age groups and
seropositive cases.
Results: 800 blood samples were collected from different age groups of hospitalized patients and analyzed. 18.8%
(n=151) cases were observed seropositive. 25.7% (n=61) seropositive cases were in age group 16-30 years followed
by 19.5% in age group from 61-75 years. Statistical significant correlation was observed among seropositive IgG
cases and age group ranging between 16-45 in female and above 45 in males.
Conclusion: This study concluded 18.8% seroprevalence among asymptomatic admitted patients. The criteria of
herd immunity is not fulfilled but it can be used for further research. The chance of seropositivity in females
during reproductive age group is more as compared to other age groups.
Mehveen Iqbal, Atiya Batool Gardezi, Shanila Feroz, KauserMehmood, Sabiha Mirza, Ejaz Ahmed. (2020) Seroprevalence OF Antibodies against SARS-COV2, International Journal of Pathology, Volume-18, Issue-4.
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