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Lambda cyhalothrin was tested for its adverse effects in developing fetuses of mice. Different dose concentrations of the insecticide (5.00µg/g, 10.00µg/g and 15.00µg/g BW) were given orally to the pregnant female mice on day 6, 7 and 8 of gestation. A vehicle control was maintained by giving only 0.1ml corn oil to the mothers. Fetuses were recovered on day “18”of gestation. Developmental defects like micromelia, dysplasia and short tail were observed in the treated groups. The morphometric parameters included body weight, crown rump length, brain size, length and width of eye. Morphometric values were subjected to analysis of variance to observe significance difference against control. The present study indicates that administration of lambda cyhalothrin exerts potentially adverse effects on the development of mice fetuses
Muhammad Khalil Ahmad Khan, Muhammad Zafar, Munazza Perveen, Shagufta Andleeb, Chaman Ara, Khurram Shahzad , Asmatullah. (2014) Developmental defects induced by lambda cyhalothrin in mice, Punjab University Journal of Zoology, Volume 29, Issue 2.
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