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Effects of testosterone, on regeneration of muscle fibres within rat Extensor digitorum longus (EDL) muscle grafts were studied under various experimental conditions. It was discovered ' that the muscle grafts reacted negatively to lack of androgens. The RNA and total protein contents of the grafts in the gonadectomized rats were less than those found in controls. EDL muscle grafts in testosterone propionate replaced rats developed much better than those in the androgen deprived ones. These results suggest that mammalian skeletal muscle is, in general, sensitive to the presence or absence of androgens while regenerating following free transplantation

JAVED I. QAZI , SHAHZAD A. MUFTI. (1997) EFFECTS OF ANDROGENS ON NUCLEIC ACIDS AND PROTEIN CONTENTS IN REGENERATING EXTENSOR DIGITORUM LONGUS MUSCLE FOLLOWING ORTHOTOPIC TRANSPLANTATION IN RATS, Punjab University Journal of Zoology, Volume 12, Issue 1.
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