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Background: Children often require sedation for long non-invasive diagnostic procedures. Dexmedetomidine is a highly selective alpha 2-adrenoceptor agonist with sedative, anxiolytic and analgesic properties. It mimics natural sleep and allows patients to easily arouse with minimal effects on respiration and airway patency.
Objective: To assess the successful completion of pediatric non-invasive diagnostic procedures with intranasal dexmedetomidine as a sedative agent.
Methods: Seventy-nine subjects of age six months to twelve years scheduled for non-invasive diagnostic procedures were included. Dexmedetornidine (4 mcg/kg) was administered intranasally 25 minutes before the scheduled time of procedure. A sedation score of two or above as per the MICHIGAN sedation scale was considered satisfactory for starting the procedure.
Results: Seventy-four (95%) out of the seventy-nine subjects were successfully sedated with Intranasal dexmedetomidine (p<0.0001). The mean time and Standard deviation to achieve sedation was 18.9 2.82 mins. The median time was 19 mins with a range from 15-25 minutes. Post anesthesia discharge time for Intranasal dexmedetomidine was 20 minutes with zero incidence of post procedure nausea and vomiting.
Conclusions: Intranasal dexrnedetoinidine can be used as an alternative to General anesthesia for non-invasive diagnostic procedures outside operating room with less adverse effects in this cohort.
Corresponding Author I Dr. Ahmed Bilal Akhtar, Shuakat Khaunm Memorial Cancer Hospital & Research Center, Lahore Email: ahmedbilalakhtar 18@hotmail.corn
Ahmed Bilal Akhtar, Muhammad Khurram Ijaz, Adeel Bashir, Ahsun Waqar Khan. (2022) Intranasal Dexmedetomidine as Sedative for Non-Invasive Pediatric Diagnostic Procedures Outside Operating Room, , volume 28, issue 2.
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