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Purpose: To evaluate the side effects and effectiveness of subconjunctival bevacizumab injection in reducing corneal neovascularization.
Material and Methods: Patients selected according to inclusion and exclusion criteria were randomly allocated to either group 1 (patients were given subconjunctival bevacizumab injection) and group 2 (patients were given subconjunctival sham injection), its effectiveness in the form of decrease in neovascular area and side effects were compared between the two groups.
Results: 41 patients were included in each group. There was no statistical significance between the 2 groups in effectiveness of the subconjunctival injection as well as in the complications except decrease in the fibrinogen level which was observed in group 1.
Conclusion: Subconjunctival bevacizumab injection failed to show significant improvement in either corneal neovascularisation or visual acuity.
Nasir Bhatti, Umair Qidwai, Umer Fawad, Munawar Hussain, Aziz Ur Rehman, Mazhar Ul Hasan. (2012) Side Effects and Effectiveness of Subconjunctival Bevacizumab Injection in Patients with Corneal Neovascularization, Pakistan Journal of Ophthalmology, Volume 28, Issue 1.
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