Abstract
Objectives: Evaluate serum bilirubin in adult healthy subjects and its correlation
with white blood cells as risk factor for cardiovascular disease. Study Design: Cross- sectional
study. Setting: Department of Pharmacology and Medicine, Suleman Roshan Medical College.
Period: January - December 2017. Material & Methods: A sample of 100 male and 100 female
adult healthy subjects were recruited for study protocol. Blood glucose, Serum creatinine, Blood
lipids, liver enzyme levels, White blood cell counts and Serum bilirubin levels were analyzed.
Pearson`s correlation was used for the correlation coefficient and its statistical significance
for the association of serum bilirubin and white blood cells. Data variables were analyzed by
statistical software SPSS (ver 21.0) at 95% CI (P ≤ 0.05). Results: Mean± SD age of male and
female was found 47.02±8.42 and 48.59±7.80 years respectively (P=0.071). Serum bilirubin
shows statistically significant negative correlation with blood glucose (r= - 0.257, P=0.0001)
and LDLc (r= - 0.155, P=0.027) and WBC (r= - 0.871, P=0.0001). Conclusion: The present
study shows the elevated serum total bilirubin levels within reference range correlated negatively
with total white blood cells in adult healthy population.
Kashif Rasheed Shaikh, Shumaila Shaikh, Shagufta Memon, Umair Ali Soomro, Shumail Saeed Siddiqui, Sadia Tabassum. (2020) Serum Bilirubin level and its correlation with white blood cells as risk factor for cardiovascular disease in adult healthy population., The Professional Medical Journal, Volume 27, Issue 12.
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