Abstract
Objectives: To compare the outcome of nebulized epinephrine versus salbutamol
for the management of children presenting with bronchiolitis. Study Design: Randomized
Controlled Trial. Setting: Department of Pediatrics, Federal Government Polyclinic Hospital,
Islamabad. Period: 6 month (1st October, 2016 to 1st April, 2017). Material & Methods: Children
fulfilled selection criteria were enrolled. Then patients were randomly divided in two groups by
using lottery method. In Group A, children received salbutamol. In group B, children received
nebulized adrenaline. After 48 hours, children were evaluated for heart rate, respiratory rates,
oxygen saturation and Respiratory Distress Assessment Index (RDAI) score. All the information
was collected using proforma. Data was analyzed using SPSS version 21. Results: The mean
age of children was 10.45±6.70 months in epinephrine group and13.07±6.28 months in
salbutamol group. There were 29 (52.7%) males & 26 (47.3%) females in both groups. After 48
hours, mean heart rate was 122.58±4.75bpm with epinephrine while 127.87±4.4.44bpm with
salbutamol. Mean respiratory rate was 35.16±3.29bpm with epinephrine while 39.84±3.32bpm
with salbutamol. Mean RDAI score was 8.35±1.36 with epinephrine while 10.07±1.37 with
salbutamol. Mean oxygen saturation was 85.24±2.74% with epinephrine while 80.38±3.26%
with salbutamol. The difference was significant (P<0.05). Conclusion: Thus the nebulized
epinephrine was found to be more effective in maintaining heart rate, respiratory rate, oxygen
saturation and RDAI score of children as compared to salbutamol.
Ana Farooq, Tehmina Maqbool, Samia Aslam, Muhammad Ahsan, Muhammad Alam Khan , Mydah Tariq, Malik Abid Ali. (2020) Nebulized epinephrine versus salbutamol for the management of children presenting with bronchiolitis: Single Center Study., The Professional Medical Journal, Volume 27, Issue 12.
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