Abstract
Background: In patients with liver cirrhosis due to Hepatitis C virus, impaired renal haemodynamics
leads to disturbance of glomerular filtration rate, real time estimation of renal haemodynamics can be
assisted using renal Doppler. The aim of this study was to determine the correlation between renal
resistive index (RI) and serum creatinine for evaluation of renal function in patients with Hepatitis C
infection. Methods: This cross-sectional research was done from 22nd November 2013 to 5
th
November 2018 at Radiology Department, Mayo Hospital, Lahore. A total of 158 Hepatitis C positive
patients divided to four groups (A, B, C, and D) according to disease stages and 79 healthy individuals
were included as control group (group E). Serum creatinine was estimated and renal resistive index
studied on colour Doppler, and correlation between serum creatinine and renal resistive index was
studied. Results: Serum creatinine levels were considerably higher among diseased groups as
compared to the control group. The highest creatinine level was observed in Group-D (1.05±0.20),
followed by group C, B and A. Similarly, mean renal resistive index was significantly higher in
diseased groups (highest: Group-D; 0.78 and 0.81 in right and left kidneys respectively). Conclusion:
Renal resistive index has positive correlation with serum creatinine level. Resistive index taken on
Doppler ultrasound can predict disease progression at an early stage, even before establishment of
clinical symptoms and derangement ofserum creatinine
Burhan Rasheed, Soban M. Daud, Saima Rasheed, Faisal Masood, Ameen Hamood Abdo Rageh. (2020) RENAL DOPPLER ULTRASOUND AS PREDICTOR OF RENAL IMPAIRMENT IN PATIENTS WITH HEPATITIS C AND ITS CORRELATION WITH SERUM CREATININE, Pakistan Journal of Physiology, Volume 16, Issue 2.
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