Association of acute myeloid leukaemia with bone marrow plasmacytosis is a rare phenomenon with diverse
underlying pathogenetic mechanisms. We report a case of a 75 years old diabetic male diagnosed as suffering
with plasmacytosis. There were no lytic bone lesions or Bence‐Jones proteinuria. Serum protein
electrophoresis did not show a monoclonal band. A presumptive diagnosis of AML with reactive plasmacytosis
was made. Possible conditions which can be considered in differential diagnosis are discussed.
