Abstract
OBJECTIVE: To determine the frequency of Malnutrition Inflammation Complex Syndrome
(MICS) in patients with End Stage kidney disease on maintenance hemodialysis patients presenting to tertiary care Hospital in Karachi.
DESIGN: A cross sectional study
SETTINGS: Department of Nephrology Jinnah Postgraduate Medical Center, Karachi
METHODS: Total of 62 patients was included through non-probability purposive sampling. All
patients diagnosed with End stage kidney disease on maintenance hemodialysis (twice week
for >3months) were included and patients with acute kidney injury, chronic infections and
chronic liver disease were excluded. Malnutrition inflammation score (MIS) was used to determine malnutrition inflammation complex syndrome (MICS). Mean and standard deviation were
calculated for continuous variables, and percentages or proportions for categorical variables.
Chi square test was used to determine the proportion of MICS in Maintenance Hemodialysis patients.
RESULTS: Mean age was 46 years ±12.59 SD (range 18-72 years). 34 (55%) were females and 28
(45%) males. 26 (42%) patients had duration of Maintenance Hemodialysis<1 years and 28(45%)
between 1-4 years. Frequency of malnutrition complex syndrome (MICS) in patients with end
stage renal failure was noted in 60 (97%) patients, out of these 31(50%) patients had mild MICS
and 29 (47%) patients moderate MICS. Mild and Moderate malnutrition complex syndrome
(MICS) was more observed in age group of 31-40years (12% in mild and 14% in moderate
MCIS).Moderate MICS was higher in females and mild MICS was higher in male patients.
CONCLUSION: Our study concluded that most (97%) of our patients with end stage kidney disease on maintenance hemodialysis has evidence of malnutrition inflammation complex syndrome.
Kaneez Zehra, Pooran Mal, Dileep Kumar , Abdul Mannan Junejo. (2014) Frequency of Malnutrition Inflammation Complex Syndrome in Patients with End Stage Kidney Disease on Maintenance Hemodialysis Presenting to Tertiary Care Hospital, Karachi, Journal of Liaquat University of Medical and Health Sciences, Volume-13, Issue-3.
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