Abstract
Healthcare system is experiencing a paradigm shift to precision medicine. Genotypic–phenotypic affiliation has
been found to be a fundamental percept in biology after the completion of Human Genome project. The first
era of precision medicine is now split into groups and subgroups, making it a meaningful strategy concurrently
throughout the clinical phases of drug designing and development. It likewise recommends healthcare
reshaping that suggest disease perceptivity or remedial treatment. Thus, translational genomics addresses
bench to bedside approach to achieve P4 medicine (personalized, predictive, preventive, and participatory),
i.e., early disease diagnosis and specifically designed treating plans instead of one size fits all.
Fouzia Shaikh, Talat Mirza. (2021) Molecular Pathology: A Paradigm Shift towards Precision Medicine, The Pakistan Journal of Medicine and Dentistry, Volume 10, Issue-1.
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