Abstract
Objective: To determine the frequency of renal failure among the Covid-19 infected patients and to explore clinical consequences among them by assessing the frequency of respiratory support, general symptoms, sequential organ failure assessment score, and mortality rate.
Study Design: A cross-sectional analytical study.
Place and Duration: From 1ST June 2020 to 1ST December 2020 at Covid ward of Nishtar Medical University and Hospital Multan.
Methodology: After confirmation of SARS-CoV-2 infection through Real-time RT-PCR, Patients were regularly evaluated for serum creatinine level, in compliance with the Kidney Disease Improving Global Outcomes guidelines. Based on creatinine level, patients were categorized into two groups: Group A comprised of patients who developed acute renal failure while group B consisted of patients whose renal system remained intact. The two groups were then observed during their covid-19 course for the development of associated symptoms, laboratory findings, and development of any complexity. Afterward, the sequential organ failure assessment score (SOFA) was calculated
Results: Out of the total studied population (n=158) , 18.1% of patients were positive for covid-19 and renal failure. There was no significant difference between underlying comorbidities and general covid-19 symptoms between the two study groups. However, renal failure patients recorded significantly high values of CRP (57mg/L±11 vs 45.9mg/L±8) and a significant number (p<0.05) required various means of respiratory support. 8.6% of renal failure patients in contrast to 20.6% suffered shock. A higher rate of mortality (p=0.03) was observed among covid-19 patients who developed renal failure.
Conclusion: A significantly high percentage of covid-19 infected patients develop renal failure and not only suffered from severe clinical outcomes but also had a high mortality rate.
Keywords: Renal failure, Renal injury, Covid-19, In-hospital consequences, Infection, Mortality.
How to Cite This:
Khalid P, Wazir Z, Khan FY, Abbas G, Khan L, Rehman FU. Covid 19 and renal failure: Likelihood of development of renal failure among Covid-19 patients and its clinical consequences. Isra Med J. 2021; 13(3): 163-166.
Zahid Wazir, Poonum Khalid, Farah Yasmin Khan, Ghulam Abbas, Lateef Khan, Fazal-ur-Rehman. (2021) Covid 19 and renal failure: Likelihood of development of renal failure among Covid-19 patients and its clinical consequences, Isra Medical Journal, Volume 13, Issue 03.
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