Abstract
Extensor digitorum longus (EDL) muscle was transplanted in control,
streptozotocin diabetic, insulin replaced and hyperinsulinaemic rats. Total number of regenerated muscle fibers in four week old control EDL muscle grafts turned out to be 4202±496.88. Three-week old grafts in the diabetic rats had significantly lesser number of regenerated muscle fibers than the respective control value. In insulin replaced rats the number of fibers did not differ significantly from control as well as the diabetic rats. Oneweek-old EDL muscle grafts in insulin replaced rats had significantly higher glycogenic fibers than the other two categories of the respective transplants. Hyperinsulienaemia caused hyperplasia at 2-week stage. Hyperinsulinaemia promoted the frequency of glycogenic fibers to some extent within the muscle regenerate
JAVED IQBAL QAZI, NADIA ILYAS , SHAHZAD AHMAD MUFTI. (2005) EFFECTS OF DIABETES AND HYPERINSULINAEMIA ON NUMBER OF REGENERATED MUSCLE FIBERS AND THEIR GLYCOGEN CONTENT IN EXTENSOR DIGITORUM LONGUS MUSCLE TRANSPLANTS , Punjab University Journal of Zoology, Volume 20, Issue 2.
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