Abstract
This project was carried out to study immunopathological and haematological effects of experimental E. coil infection in broiler chicks. For this purpose one hundred (day-old) broiler chicks were randomly divided in two equal groups A and B on day-21 of the experiment. At the same day chicks of group A were inoculated with confirmed pathogenic isolate (3x107 bacilli/0.1 ml) of E. coil intraperitoneally while chicks of group B received sterile nutrient broth and acted as control. Result showed that haemoglobin (1-1b), packed cell volume (PCV). Total erythrocyte count (TEC), antibody titre against Newcastle disease virus (NDV) and feed conversion ratio (FCR) were significantly lower while total leukocyte count (TLC) was significantly higher in treatment than control group on all the three sampling days. Moderate to marked gross and microscopic pathological changes in heart, liver and spleen were also observed in treatment group as compared to control one. Mean lymphoid organs weight/body weight ratio and post-infection mortality were higher in treatment group as compared to control one. From the foregoing study it was concluded that infection with E. coli resulted not only in haematological and pathological alterations but it also impaired the immune system along with high mortality in infected birds
MUHAMMAD FAROOQ RAI, MANSUR-UD-DIN AHMAD , TANVEER AKHTAR, AZHAR MAQBOOL , RANA SAJJAD AHMAD. (2004) STUDIES ON THE IMMUNOPATHOLOGY AND HAENIA TOLOGY OF BROILERS EXPERIMENTALLY INFECTED WITH ESCHERICHIA COLI , Punjab University Journal of Zoology, Volume 19, Issue .
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