Low dose radiation-induced damages to DNA are mainly repaired by poly (ADP-ribose) polymerase (PARP-1 and PARP-2) system present in the cell. Suppression of neoplastic transformation of human hybrid cells by low doses of low linear energy transfer (LET) radiation is abrogated by PARP enzyme inhibitors and this presents a new tool in radiotherapy for cancers. The aim of this study was to investigate DNA damages by low doses of gamma rays (2.4 mGy/h) in the presence of inhibitors, 3-aminobenzamide (3-AB) and DPLQRQDSKWKDOLPLGH
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