Abstract
A study was carried out to determine blood groups of a random population sample from urban and rural areas of Sahiwal district, Punjab province, Pakistan. Blood samples were collected from the patients visiting to the DHQ Hospital Sahiwal. A total of 20,010 subjects, comprising 3,901 (19.5%) female and 16,109 (80.5%) males, were screened for blood grouping. The objective of this study was to determine the frequency of different blood groups in this District, which would helpful in blood transfusion, organ transplantation, erythroblastosis fetalis, glaucoma and certain other diseases. The distribution of phenotypic frequencies for ABO group in the total sample were 22.0%, 36.9%, 9.9% and 31.3% for groups A, B, AB and O, respectively, while 87.1% of the subjects were Rhpositive. The calculated allelic frequencies were 0.182, 0.276 and 0.541, for group A, B and O, respectively, and 0.357 for d allele. From these studies it is concluded that phenotypically B group was dominant in both genders of the Sahiwal District with high allelic frequency of O group. These studies revealed that the gene frequencies in Sahiwal district are: O>B>A>AB
