Abstract
Introduction: Tinea corporis also known as ‘ringworm’ is dermatophytosis of the trunk. It usually presents as an annular plaque with a slightly raised and often scaly, advancing border. Topical azoles in combination with steroids are commonly prescribed. But it is unclear whether they are superior to topical azoles alone or not.
Objective: To compare the clinical efficacy of 1% topical clotrimazole cream vs combination of 1% isoconazolenitrate (ISN)with 0.1%diflucortolone valerate (DFV) cream in patients of tinea corporis.
Methods : A randomized controlled trial was performedon 380 patients of outdoor dermatology unit of Pakistan Institute of Medical Sciences, Islamabad. They were randomly allocated to two groups by lottery method named Group A who were given topical 1% clotrimazole cream (an antifungal) and Group B who were given topical 1% isoconazole nitrate (an antifungal) and 0.1% diflucortolone valerate cream (a corticosteroid). Both groups were asked to apply respective cream twice daily for two weeks.
shawana sharif , syed afaq ahmad , faiza aslam. (2018) CLINICAL EFFICACY OF TOPICAL CLOTRIMAZOLE VERSUS COMBINATION OF ISOCONAZOLE NITRATE WITH DIFLUCORTOLONE VALERATE IN TINEA CORPORIS, International Journal of Pathology, volume16, jul-sep.
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