Abstract
OBJECTIVE: To determine the frequency of common microorganisms
involved in chronic suppurative otitis media (CSOM) and their antibiotic
sensitivity.
METHODS: This cross sectional study of 776 patients suffering with CSOM
was conducted at Otolaryngology Department, Ayub Teaching Hospital,
th th Abbottabad from 5 May 2017 to 5 November 2018. Patients fulfilling the
inclusion criteria were enrolled for otoscopic examination. Sterile cotton swabs
were used to collect pus samples and were sent to microbiological analysis and
antibiotics sensitivity.
RESULTS: The age ranges of the patients were from 13-73 years, with a mean
age of 28.98±13.40 years. The incidence of CSOM was highest in 21-30 years
age group (294~37.9%). In a total 776 CSOM patients, only 501 (64.56%) of
the samples showed microbial growth. In aerobic isolates, the most common
bacterium was Pseudomonas aeruginosa (30.7%) followed by Staphylococcus
aureus (11.1%) including 6.7% MRSA. Anaerobes were isolated in 1.2% of the
samples in which bacteriodes were being the most common. Samples (1.8%)
showed fungal growth and yielded only Candida spp while 0.5% samples were
positive for acid fact bacilli. In antimicrobial sensitivity investigation Pseudomonas
aeruginosa showed highest sensitivity to piperacillin/tazobactum (84%), to
levofloxacin (25.21%), to ciprofloxacin (20.59%). The highest sensitivity of
Staphylococcus aureus was investigated for piperacillin/tazobactum and
ceftazidime with 91.18%, and showed no sensitivity to ciprofloxacin and
levofloxacin.
CONCLUSION: Pseudomonas aeruginosa and Staphylococcus aureus were the
most common bacteria. Both show increasingly high resistance to quinolones
and amino glycosides, but both isolates are sensitive to piperacillin/tazobactum,
imipenam, cefoperazone/salbactum and ceftazidime.
Muhammad Ibrahim, Syed Maisam Ali, Muhammad Imran Shah, Muhammad Abkar Khan. (2019) MICROORGANISMS PROFILE AND ANTI-MICROBIAL SENSITIVITY IN CHRONIC SUPPURATIVE OTITIS MEDIA, KHYBER MEDICAL UNIVERSITY JOURNAL, Volume 11, Issue 4.
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