Abstract
PURPOSE:
To study the mean loss of corneal endothelial cell in patients undergoing
cataract surgery with phacoemulsification with and without trypan blue.
STUDY DESIGN:
Randomized controlled trial
PLACE AND DURATION OF STUDY:
Institute of Ophthalmology, Mayo Hospital/ King Edward Medical University,
Lahore.
From 1-1-2016 to 30-5-2017
MATERIAL AND METHODS:
152 patients presenting to the Institute of Ophthalmology were included in
study. Patients diagnosed with cataract were selected for surgery. The
patients were divided into two groups A and B. Group A patients underwent
phacoemulsification with trypan blue aided central curvilinear capsulorhexis
while Group B patients underwent phacoemulsification without any aid of
trypan blue. Patients with any corneal opacity were excluded from study.
Specular microscopy was done on all patients before and three months after
surgery. On specular microscopy, corneal endothelial count, hexagonality
and coefficient of variation were noted. Specular microscopy and recording
of findings was done by researcher.
RESULTS:
Endothelial cell loss was observed in both the groups but it was more
in the Group A (74.3421±0.6332)as compared to the Group B
(37.0658±2.6891) (p 0.000).
CONCLUSION:
Phacoemulsification decreases corneal endothelial cell count both with and
without trypan blue. The decrease in corneal endothelial cell count was more
when phacoemulsification was done with trypan blue but it did not lead to
corneal decompensation.
KEY WORDS:
Phacoemulsification, Trypan Blue, Corneal Endothelial Cell Count.
Arooj Amjad, Muhammad Shaheer, Ummarah Rasheed. (2017) Corneal Endothelial Cell Loss after Phacoemulsification with and without Trypan Blue � 218 Assisted Staining of Anterior Lens Capsule, Pakistan Journal of Ophthalmology, Volume 33, Issue 4.
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