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BENZIMIDAZOLE DERIVATIVES WITH POTENTIAL CYTOTOXIC ACTIVITY -SYNTHESIS AND THEIR STRUCTURE-ACTIVITY RELATIONSHIP

Abstract

Benzimidazole is an important class of compounds with a wide spectrum of biological activity. This five membered heterocyclic moiety confer for various biological activities. In this study, we prepared some benzimidazole derivatives of 2-(2´-pyridyl) benzimidazole and investigated their cytotoxic effect. The structure of the synthesized analogs were characterized by UV, IR and 1H NMR spectral data and evaluated for their cytotoxic effect.

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ARFA KAMIL, SHAMIM AKHTAR, ANEELA KARIM, AHSAAN AHMED, MEHWISH WAJDI, ZAHID KHAN, ZAHID KHAN, SAEED SAIFY. (2013) BENZIMIDAZOLE DERIVATIVES WITH POTENTIAL CYTOTOXIC ACTIVITY -SYNTHESIS AND THEIR STRUCTURE-ACTIVITY RELATIONSHIP, fuuast Journal of Biology, Volume 3, Issue 2.

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Article Details

Journal

fuuast Journal of Biology

Volume

Volume 3

Issue

Issue 2

Type

Regular

Language

English

Received At

2019/01/11

Accepted At

1970/00/01

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