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As an alternative of antibiotic growth promoters, medicinal plants are the most popular options. Papaya leaves are good source of vitamins, minerals, antioxidants and enzymes which provide aid in digestion of carbohydrates, proteins and fats and overcome the microbial load and used as a growth promoter and antibiotic in broiler performance. This study was carried out in order to evaluate the effect of papaya leaf extract in drinking water as a replacement of commercial antibiotic on blood hematology, serum biochemistry and immune response of broilers for the duration of 35 days. Methods: In this experiment, 180 one-day old chicks were randomly distributed into 6 treatments. Each treatment was divided into 3 replicates having 10 chicks each. Feed was offered ad-libitum to broilers. Six treatments; G1 {(basal diet + antibiotic growth promoter (enramycin) + coccidiostat (salinomycin)}, G2 (basal diet without antibiotic growth promotor and coccidiostat), G3 (basal diet + 0.5% papaya extract), G4 (basal diet + 1.0% papaya extract), G5 (basal diet + 1.5% papaya extract) and G6 (basal diet + 2.0% papaya extract) were designed. Blood samples were taken for serum biochemistry, hematology and titer against Newcastle disease. Data were analyzed using analysis of variance technique by completely randomized design using SAS and Tukey’s test were used for comparison of means. Results: Birds received various level of papaya extract had no effect on serum biochemistry and hematology parameters except triglyceride levels which were significantly lower in G2 (15.00±15.00, commercial diet) and G6 (17.43±9.87, commercial diet + 2% papaya extract) at 17th day and 35th day where it failed to show significant difference. However, Newcastle disease and infectious bursal disease titers were not affected by the treatments.

Muhammad Khalid Bashir, Muhammad Ashraf, Shahid Ur-Rehman, Sadia Razzaq, Muhammad Qamar Bilal, Sayeda Mariam, Madiha Tabbasum. (2019) Effects of Carica Papaya Leaf Extract on Blood Hematology, Serum Biochemistry and Immune Response of Broilers, Advancements in Life Sciences, Volume 7, Issue 4.
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