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Multi-drug-resistant tuberculosis (MDR-TB) is a threat to global health. In 2018, TB related death was
estimated to be more than 1.5 million cases worldwide. Conventional diagnostic method, which requires
a long time to get a result, causes delays in new cases discoveries that lead to delayed therapy. Further,
delayed and inadequate therapy causes an increase in the level of resistance to anti-TB drugs that may lead to
death. Therefore, diagnostic tools, which can detect quickly and accurately, are highly needed. Early and timely
detection is crucial for globally effective TB control, but this is not popular in developing countries, especially in
Asia. Therefore, the objective of this review is to provide current information on the use of NGS as a rapid
diagnostic tool for MDR-TB, especially in Asian populations, and to highlight the various MDR genes.
Anse Diana Valentiene Messah, Jeanne Adiwinata Pawitan. (2020-2021) Next Generation Sequencing as Rapid Diagnosis of Multidrug Resistance Tuberculosis, Advancements in Life Sciences, Volume-8, Issue-1.
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