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Ruminants are common victims of helminthic infections which curb the efficient production of
livestock. Chemical anthelmintic are used to control parasitic infections but their persistent use develop
resistance in parasites. In this connection local plants/ their parts are being used to explore their anthelmintic
potential. The aim of the present study was to determine the anthelmintic activity of Tribulus terrestris L. and
Ziziphus mauritiana Lam. Whole plant of Tribulus terrestris L. and leaves of Ziziphus mauritiana Lam. were
used. The plant materials were dried, ground firmly, macerated in ethanol and then the crude ethanolic
extract (CEE) was prepared. Adult motility assay (AMA) was carried out on adult Haemonchus contortus to
analyze the anthelmintic efficacy of CEE of the whole plant and the leaves of Tribulus terrestris L and
Ziziphus mauritiana Lam. The motility of insects was assessed at concentration of 2, 4, 6 & 8 mg/ml after 2,
4, 6 & 8 hours of post treatment and dead worms were noted. The 8mg/ml concentration of CEE of Tribulus
terrestris L. and Ziziphus mauritiana Lam. exhibited 90% and 93% mortality rate, respectively, after 8 hours
of post treatment. The positive control, levamisole showed 100% mortality at 0.5mg/ml concentration. It is
concluded that Tribulus terrestris L. and Ziziphus mauritiana Lam. possess wormicidal potential and their
extracts have anthelmintic activity against Haemonchosis contortus
ABRAR HUSSAIN, AQSA KHALIL, SAIRA ZAHEER, MUHAMMAD LATEEF, MUHAMMAD MANSHA. (2018) In vitro efficacy of Tribulus terretris L. & Ziziphus mauritiana Lam. as potential anthelmintics against Haemonchosis contortus, Biologia – Journal of Biological Society of Pakistan, Volume 64 (I), Volume 64 (I).
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