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The pyrethroid group of pesticides, which include deltamethrin, is preferably used for pest control programs as a replacement for organochlorines and organophosphates group of pesticides, as it has comparatively low toxicity and has low persistence in the environment. Deltamethrin is highly toxic to aquatic organisms including fishes as compared to terrestrial animals. The present study was carried out to explore the lethal effects of deltamethrin on spleen and kidney of silver carp. Numerous histological changes were observed in kidney and spleen of fish after acute exposure to pesticide. Doses were 25%, 50% and 75% of LC50. Histopathological changes like damage in tissues of spleen and kidney became severe with increasing dose concentration. Most pronounced histopathological changes in kidney included degeneration of renal tubules, dilatation of glomerular capillaries, degeneration of glomeruli, narrowing of the tubular lumen, and atrophy and lyses of glomerular tufts. Spleen of treated fish showed necrosis and significant changes in number of melanomacrophage centres as compared to control.

ASMA KARIM, NOREEN AHMAD , WAJID ALI. (2016) Histopathological Changes in Spleen and Kidney of Silver carp (Hypophthalmicthys molitrix) after Acute Exposure to Deltamethrin, Biologia – Journal of Biological Society of Pakistan, Volume 62 (I), Issue 1.
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