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Spider venom comprises of 10 million bioactive peptides but only 800 peptides are pharmacologically
characterized. Despite this limited number of characterized peptides, the range of biological activities they
perform is incredible. Their venom is able to potently block a variety of receptors, channels, enzymes and other
various target sites. Therefore, it is not surprising that the peptides extracted from spider venom possess
substantial potential for therapeutic applications. This review article encompasses the potential applications of
spider venom as analgesics, anti-fungal, anti-parasitic and anti-bacterial agent, and bio-insecticides. Moreover,
some of the venom peptides have marked antiarrhythmic and neuroprotective potentials. With these potentials
spider venom could be utilized in development of prototypes for pharmaceutical applications.
HAFIZ MUHAMMAD TAHIR, AROOJ ZAHEER, RABIA YAQOOB, ABDUL KHALIQ, KHANUM ZAHRA. (2016) Applications of Spider Venom in Medical Science and Agriculture, Biologia – Journal of Biological Society of Pakistan, Volume 62 (I), Issue 1.
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