Abstract
Goiter is a disease physically shown by abnormal enlargement
of neck. In such cases, thyroid gland cannot synthesize adequate amounts of tri-iodothyronine (T3) and thyroxin (T4) hormones. The blood never carries enough of thyroid hormones to shut off the secretions of thyroid stimulating hormone (TSH) by the hypothalamus. The clinical
manifestations are hoarseness, reflex delay, infertility, dry skin, memory
and mental retardation. Normal T3 level in blood is 1.1–2.7 nmol/L, T4 is
8.0-21.0 pmol/L and TSH ranging from 0.4-4.0 mlU/L. It was measured
that the level of thyroidal hormones except TSH becomes high in goitrous
patients. The present study was planned to investigate the concentration
levels of thyroid hormones (T3, T4) and TSH of goitrous female of local
population. Total 30 subjects (15 normal and 15 goitrous females) were
studied. Biochemical tests were done and the data collected was analyzed
statistically. Mean levels of T3 (3.43±0.15 nmol/L) and T4 (26.6±1.58
pmol/L) in goitrous were significantly higher as compared to normal
while the level of TSH (0.92 mlU/L) was significantly low in goitrous
compared to normal subjects. These results suggested that goitrous
females have hyperthyroidism.
SUMARIA SIDDIQUE, ABDUL QAYYUM NAYYER, SHAUKAT ALI , HAFIZ ABDULLAH SHAKIR. (2010) ASSESSMENT OF T3, T4 AND TSH OF GOITROUS FEMALE POPULATION AT BANJOSA, AZAD JAMMU AND KASHMIR , Punjab University Journal of Zoology, Volume 25, Issue (1&2).
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