Abstract
OBJECTIVE: To record the clinical and demographic characteristics of measles
in patients hospitalized with measles infection in Peshawar, Pakistan.
METHODS: A retrospective review of medical records from December 2016
to January 2017 was conducted at Northwest General Hospital and Research
Centre, Peshawar. A total of 182 measles patients' data was retrieved and
recorded in predesigned format which included information on demographics,
clinical features, complications and outcome. Both descriptive and inferential
statistics were used for data analysis.
RESULTS: Out of 182 patients, 118(64.8%) were males. The mean age was
24.1±2.5 months. The average length of hospital stay was 3.09±2.58 days. The
most common complication was pneumonia 99 (54.4%), followed by diarrhea
54 (29.7%) and encephalitis 11 (6.0%). The patients were categorized in to two
age groups, pre-vaccination group (≤9 months age) and post-vaccination group
(>9 months age). Significant number of cases 54 (30%) were seen in age group
<9 months. Only 45 (35%) cases in age group >9 months received the
scheduled measles vaccination. Multivariate regression analysis revealed that
presence of Koplik spots [AOR=0.251, Cl; 0.074-0.853, p=0.027], high
lymphocyte count [AOR=0.205, Cl; 0.092-0.453, p<0.001] and being
unvaccinated in general [AOR= 2.546, Cl; 1.185-5.469, p=0.017] were found
to be significantly associated with age group >9 months. Majority of patients
were from the Peshawar (n=95) followed by Kohat (n=10),
CONCLUSION: Pneumonia was the commonest complication followed by
diarrhea. Vaccination history was very poor and significant number of patients
were seen in age group <9 months of age.
Faheemullah Khan, Amin Jan Gandapur, Iftikhar Ali, Rifaq Zeb, Wiqar Ahmad. (2019) CLINICAL AND DEMOGRAPHIC PROFILE OF CHILDREN HOSPITALIZED WITH MEASLES INFECTION IN PESHAWAR, PAKISTAN, KHYBER MEDICAL UNIVERSITY JOURNAL, Volume 11, Issue 2.
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