A study was conducted for the detection of Balantidium coli and to determine the comparative efficacy of
ampicillin, secnidazole and neem seeds (Melia Azadarch linn) against balantidiosis in buffaloes around Lahore. A
total of two hundred buffaloes were examined coprologically. Of those, 40 were found positive (20%), twenty-four
buffaloes having balantidiosis were selected for chemotherapeutic trials and were divided into four equal groups.
The efficacy of drugs was determined on the basis of disappearance of clinical signs and reduction of
cysts/trophozoites in faeces. It was concluded that secnidazole (Dysen forte) is the drug of choice for the
treatment of bovine balantidiosis.