Abstract
Gene expression regulation is an important molecular process for
monitoring overall expression level of genes in plants. The expression of
genes is regulated by certain regulatory elements including, Cis-acting
regulatory elements (CRE), transcription factors (TFs) and promoters.
Cis-acting elements are actually specific class of DNA binding proteins
that act at particular site of DNA. Promoters are part of DNA fragment
essential for transcriptional regulation of genes with certain transcription
factors. These transcription factors could be useful in developmental
regulation, interpretation and validation of candidate genes. This review
highlights the importance of Cis-acting regulatory elements and
transcription factors for regulation of gene expression. Furthermore, the
use of bioinformatics approach for identification of transcription factors
and putative motifs within the promoter region has gained much success
for studying DNA-protein interactions. These findings promote the
importance of CRE and TF inactivation of transcriptional networks for
enhanced gene expression studies in plants.
HIRA MUBEEN, AMMARA NASEEM, AMMARA MASOOD, SHAHID RAZA, NAUREEN NAEEM. (2018) Cis-acting regulatory elements and transcription factors as a key regulator in plant gene expression, Biologia – Journal of Biological Society of Pakistan, Volume 64 (II), Volume 64 (II).
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