Abstract
Meat industry produces huge amount of waste which have potential to be used as the valuable source of proteins and derived
bioactive compounds. Dietary interventions have augmented the use of bioactive components with increased awareness for
healthy life of individuals. Efforts have been endured to develop functional constituents that offer therapeutic responses
towards physiological disorders. The current study was designed to investigate the therapeutic potential of meat byproducts
hydrolysates derived after enzymatic hydrolysis with special reference to anti-hypertension and antioxidant activity. Meat
byproducts were subjected to physicochemical assays and hydrolysis assessment were also carried out to estimate the release
of peptides through RP-HPLC. Moreover, the hydrolysates containing bioactive peptides obtained after hydrolyses were
further evaluated for antihypertensive and antioxidative activities. Liver and kidney showed higher enzymatic hydrolysis at
maximum hydrolysis time. The ACE inhibitory activity of liver hydrolysate increased significantly with increase in
hydrolysis time. The kidney hydrolysates have significantly higher ABTS radicals scavenging activity than liver and heart.
The results indicated that hydrolysates of liver and kidney showed significantly higher oxygen radical absorbance capacity
(ORAC) activity after given hydrolysis time. In conclusion, meat byproducts can be utilized for generation of functional
bioactive peptides that therapeutic applications to cure human ailments.
Munazza Saeed, Muhammad Issa Khan, Masood Sadiq Butt, Farah Riaz. (2020) CHARACTERIZATION OF PEPTIDES FRACTIONS PRODUCED THROUGH ENZYMATIC HYDROLYSIS OF MEAT BYPRODUCTS FOR THEIR ANTIHYPERTENSIVE AND ANTIOXIDANT ACTIVITIES, Pakistan Journal of Agricultural Sciences, Volume 57, Issue 2.
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